This white paper examines challenges for healthcare organizations and presents how the key to effective endpoint and server protection lies in the ability to dynamically analyze behavior in order to recognize malicious software by its actions, not its appearance. Intelligent response at machine speed is required to prevent, contain and mitigate potential threats. Success in this mission results in a major benefit for providers and payers: the ability to keep IT systems operation so medical and non-medical personnel can stay focused on patient care.